Place your fingers on the home keys of your keyboard (ASDF and JKL;), which will function as the ASETNIOP primary keys (ASET and NIOP). All other letters are obtained by pressing a chord (two primary keys at the same time) - just look for the desired letter, press and hold the key, and press its companion and release both to generate the letter. To press the shift key, use one of your thumbs to press one of the bottom row keys (C, V, B, N, or M) on your keyboard. Press the "clear text" button to begin. For more detailed instructions, try the tutorial.